Study of CDI (c. difficile infections) in US hospitals showed CDI declined during year 1 of the COVID-19 pandemic. Researchers compared pre-COVID (April 2019 to March 2020) with COVID (April 2020 to March 2021). CDI prevalence went down significantly from 12.2 CDI cases per 10,000 encounters, to 8.9 per 10,000. Inpatient costs however were about $2,000 higher per case – up about 19%. Inpatient mortality was also higher – 7.4% compared to 5.5% in the pre-Covid period. Study was based on a sample of hospitals from the Premier Healthcare Database. Published in the Open Forum Infectious Diseases, August 2022.