Five most costly medical conditions in 2012 were cancer, arthritis, trauma-related disorders, mental disorders, and heart conditions. The top 5 most costly illnesses were for adults ages 18 to 64 in 2012. For seniors, COPD and asthma replaced mental disorders. Medical expenditures (payments) according to MEPS data (household component) show average costs (ages 18-64) were $8,125 for a cancer patient, $4,852 for an adult with heart disease, $2,603 per trauma patient, $1,727 for mental health care, and $1,909 for someone with arthritis. Average out of pocket payments by consumers not shown. Consumers may wish to add medical inflation since 2012 of about 31%. AHRQ Statistical Brief 471, April 2015.