The words Quarantine and Isolation have been used regularly when talking about coronavirus cases. What’s the difference? Quarantine is for people who were exposed to the virus, but not yet sick. Isolation is separating people sick with COVID-19 or coronavirus from those who are not sick. CDC describes this further. Media reporting is inconsistent. Even some public health people refer to “self-isolation” (rather than “self-quarantine”) for people who have not tested positive for the coronavirus. Consequently, the terms may still be confusing.