USNews.com identifies America’s Best Hospitals on the 2021-2022 Honor Roll. Mayo Clinic (Rochester, MN), Cleveland Clinic (OH) and UCLA Medical Center (Los Angeles) which edged out Johns Hopkins by one point, top the list of 20 US hospitals identified, who rank favorably in multiple specialties. Over 4,500 hospitals nationwide were evaluated. Check the details to see specifics for a certain illness, since one hospital may not be ranked (by US News) as best in everything. Methodology report shows how the hospitals scored. Outcomes (such as Survival/mortality rate) for Medicare patients and Structure (such as nurse staffing and ICU specialists) are two of the factors used in the rankings for most of the specialties. Reputation assessed by other physicians was the only component used for Ophthalmology, Psychiatry and Rheumatology. 2021-2022 ratings use Medicare data from calendar years 2017-2019, and HCAHPS (patient satisfaction) scores from 2019. Published July 27, 2021.